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Thursday, August 29, 2013

A new peak calling software: peakzilla

From Github

Peakzilla identifies sites of enrichment and transcription factor binding sites from transcription factor ChIP-seq and ChIP-exo experiments at hight accuracy and resolution. It is designed to perform equally well for data from any species. All necessary parameters are estimated from the data. Peakzilla is suitable for both single and paired end data from any sequencing platform.

Note that peakzilla is not suited for the identification of broad regions of enrichment (e.g. ChIP-seq for histone marks), we recommand using MACS instead: Zhang et al. Model-based Analysis of ChIP-Seq (MACS). Genome Biol (2008) 9(9):R137

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