However, recently, four papers in Science actually showed that histone modifications actually have a component of inheritance:
Causal role for inheritance of H3K27me3 in maintaining the OFF state of a Drosophila HOX gene
DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation
Propagation of Polycomb-repressed chromatin requires sequence-specific recruitment to DNA
Transgenerational transmission of environmental information in C. elegans
and one paper in Molecular Cell:
SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication
one more on Nature Genetics:
Interestingly, all the studies were carried out on model organisms: Drosophila and C.elegans!
Read this blog post if you are into this question: what is epigenetics ?
Read this blog post if you are into this question: what is epigenetics ?
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