See the links below:
http://omictools.com/differential-peak-calling/
http://omictools.com/chip-seq-and-beyond/3c-4c-5c-hi-c/hicup-s1473.html
http://omictools.com/analytical-pipelines8/
http://omictools.com/dmr/
There are too many tools out there for established high-throughput sequencing based techniques.
1. you need to know what are out there. never try to re-invent the wheel
2. choose the right one to fit your own analysis. (only if none of them does what you want to do, write a script by yourself). choose one with good documentation and is being actively developed.
This blog by Tommy Tang is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
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